What is what does it mean when ovalocytes are present?

Ovalocytes: What You Need to Know

Ovalocytes, also known as elliptocytes, are abnormally shaped red blood cells that are oval or elliptical, rather than the typical biconcave disc shape. Their presence in a blood smear can indicate a variety of underlying medical conditions.

• Hereditary Elliptocytosis (HE): This is the most common cause. It's a genetic disorder affecting the red blood cell membrane proteins. The URL for this is: Hereditary Elliptocytosis

• Iron Deficiency Anemia: A lack of iron can affect red blood cell production and shape. The URL for this is: Iron Deficiency Anemia

• Thalassemia: These are inherited blood disorders characterized by abnormal hemoglobin production. The URL for this is: Thalassemia

• Myelodysplastic Syndromes (MDS): A group of bone marrow disorders. The URL for this is: Myelodysplastic Syndromes

• Megaloblastic Anemia: Often caused by vitamin B12 or folate deficiency. The URL for this is: Megaloblastic Anemia

• Other conditions: Ovalocytes can sometimes be seen in other anemias and certain rare inherited conditions.

Important Note: The significance of ovalocytes depends on the percentage of these cells present in the blood smear and the patient's overall clinical picture. A small percentage may be insignificant, while a larger number warrants further investigation. A complete blood count (CBC) and other relevant tests are usually needed to determine the underlying cause.